BASIS FOR COMPARISON | TURNER SYNDROME | KLINEFELTER SYNDROME |
---|---|---|
Meaning | When a girl is born with the different genetic condition than the normal one, it is called as Turner syndrome, in this, there is the loss of one of the sex chromosome (XO instead of XX). | When a boy is born with the different genetic condition than the normal one, where instead of having normal XY sex chromosome, they have XXY chromosomes, it is termed as Klinefelter syndrome. |
Karyotype | Monosomy of sex chromosome (2n-1), in this only one X chromosome, is present. | Trisomy of sex chromosome (2n+1), in this XXY chromosome, are present in males. |
Occurs in | 1 in 2500 phenotypic female. | 1 in 1100 phenotypic male. |
Features or Physical appearance | 1. Females are sterile. 2. Undeveloped breasts. 3. Webbed neck, Short stature. 4. Uterus, vagina, vulva present, the absence of menstruation. 5. Testes, ovary absent or poorly developed. 6. Cardiovascular problems, hearing impairment. 7. The physical appearance of the female. | 1. Males are sterile. 2. Small testes (less production of testosterone). 3. Undeveloped sex organs like seminal vesicles, penis, vas deferens. 4. Mentally retarded. 5. Feminine characteristics, such as enlarged breasts, feminine pitched voice. 6. Long limbs. 7. Patients are thinner and taller. 8. Physical appearance is the male. |
Treatment | It is commonly treated with estrogen, growth hormones and replacement therapy. | Testosterone therapy and hormone therapy. |